Publications


See here for a comprehensive list of publications.

Selected Publications


Systems Immunology: learning the rules of the immune system.

Villani AC, Sarkizova S, Hacohen N.

Annu Rev Immunol 2018; 36: 813-842. doi: 10.1146/annurev-immunol-042617-053035.

PDF


Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes and progenitors.

Villani AC*†, Satija R*, Reynolds G, Sarkizova S, Shekhar K, Fletcher J, Griesbeck M, Butler A, Zheng S, Lazo S, Jardine L, Dixon D, Stephenson E, Nilsson E, Grundberg I, McDonald D, Filby A, Li W, De Jager PL, Rozenblatt- Rosen O, Lane AA, Haniffa M, Regev A†, Hacohen N†.

Science 2017; 356: 6335. pii: eaah4573. doi: 10.1126/science.aah4573.

PDF


Landscape of X chromosome inactivation across human tissues.

Tukiainen T, Villani AC, Yen A, Rivas MA, Marshall JL, Satija R, Aguirre M,Gauthier L, Fleharty M, Kirby A, Cummings BB, Castel SE, Karczewski KJ, Aguet F, Byrnes A, GTEx Consortium, Lappalainen T, Regev A, Ardlie KG, Hacohen N, MacArthur DG.

Nature 2017; 550(7675): 244-248. doi: 10.1038/nature24265.

PDF


Targeting individual cells by barcode in pooled sequence library.

Ranu N, Villani AC, Hacohen N, Blainey PC.

Nucleic Acids Res 2019; 47(1): e4. doi: 10.1093/nar/gky856.

PDF


Single cell RNA sequencing of human T cells.

Villani AC†, Karthik Shekhar†.

Methods in Molecular Biology 2017; 1514: 203-239.


A transcriptomic atlas of aged human microglia informs neurodegenerative disease studies.

Olah M*, Patrick E*, Villani AC*, Xu J, White CC, Ryan KJ, Piehowski P, Kapasi A, Nejad P, Cimpean M, Connor S, Yung CJ, Frangieh M, McHenry A, Elyaman W, Petyuk V, Schneider JA, Bennett DA, De Jager PL, Brashaw EM.

Nat Communications 2018; 9(1): 539.

PDF


Targeting the CBM complex causes T(reg) cells to prime tumours for immune checkpoint therapy.

Di Pilato M, Kim EY, Cadilha BL, Prüßmann JN, Nasrallah MN, Seruggia D, Usmani SM, Misale S, Zappulli V, Carrizosa E, Mani V, Ligorio M, Warner RD, Medoff BD, Marangoni F, Villani AC, Mempel TR.

Nature 2019; 570(7759):112-116.

PDF


*Co-first authorship †Co-senior authorship